Dimethyl fumarate inhibits osteoclastsviaattenuation of reactive oxygen species signalling by augmented antioxidation
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چکیده
منابع مشابه
Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signalling by augmented antioxidation
Bone destructive diseases are common worldwide and are caused by dysregulation of osteoclast formation and activation. During osteoclastogenesis, reactive oxygen species (ROS) play a role in the intracellular signalling triggered by receptor activator of nuclear factor-κB ligand (RANKL) stimulation. Previously, we demonstrated that induction of antioxidant enzymes by Nrf2 activation using Nrf2-...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2017
ISSN: 1582-1838
DOI: 10.1111/jcmm.13367